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Article

Association between single-nucleotide polymorphisms of BRAF and papillary thyroid carcinoma in a Chinese population.

Thyroid : official journal of the American Thyroid Association - 1 Jan 2013

Zhang Qiang, Song Fangfang, Zheng Hong, Zhu Xiaoling, Song Fengju, Yao Xiaofeng, Zhang Lun, Chen Kexin

Abstract excerpt

BACKGROUND: Papillary thyroid cancer (PTC) is a common malignancy that frequently harbors a high prevalence of somatic mutations in the oncogenic BRAF gene. As a novel prognostic molecular marker, this gene has drawn much attention in recent years for its potential utility in the risk prognosis and management of PTC. However, the contribution of the germline variants in this gene to PTC remains unclear. The study...

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Identifiers

PMID: 22973979
DOI: 10.1089/thy.2012.0228
PMCID: PMC3539251

Genes

BRAF

Provenance

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