Article
Craniofacial anomalies in a murine model of heterozygous fibroblast growth factor 10 gene mutation.
Orthodontics & craniofacial research - 1 Feb 2024
Tan Jenny, Jones Matthew L M, Teague Warwick J, Ranjitkar Sarbin, Anderson Peter J
Abstract excerpt
OBJECTIVE: Dysregulation of Fibroblast Growth Factor 10 (FGF10), a member of the family of Fibroblast Growth Factor (FGF) proteins, has been implicated in craniofacial and dental anomalies, including craniosynostosis, cleft palate, and Lacrimo-Auriculo-Dento-Digital Syndrome. The aim of this murine study was to assess the craniofacial and dental phenotypes associated with a heterozygous FGF10 gene (FGF10+/- )...
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