Article
Skeletal dysmorphology and mineralization defects in Fgf20 KO mice.
Frontiers in endocrinology - 1 Jan 2024
Dlugosova Sylvie, Spoutil Frantisek, Madureira Trufen Carlos Eduardo, Melike Ogan Betul, Prochazkova Michaela, Fedosieieva Olha, Nickl Petr, Aranaz Novaliches Goretti, Sedlacek Radislav, Prochazka Jan
Abstract excerpt
Introduction: Fibroblast growth factor 20 (Fgf20), a member of the Fgf9 subfamily, was identified as an important regulator of bone differentiation and homeostasis processes. However, the role of Fgf20 in bone physiology has not been approached yet. Here we present a comprehensive bone phenotype analysis of mice with functional ablation of Fgf20. Methods: The study conducts an extensive analysis of Fgf20 knockout...
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