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Identification of mutation gene prognostic biomarker in multiple myeloma through gene panel exome sequencing and transcriptome analysis in Chinese population.

Computers in biology and medicine - 1 Sept 2023

Xie Chunbao, Zhong Ling, Luo Jiangrong, Luo Ji, Wu Yingmiao, Zheng Shuai, Jiang Lingxi, Zhang Jianbo, Shi Yi

Abstract excerpt

BACKGROUND: The 5-year survival rate of multiple myeloma (MM) in China is less than 40%, with considerable individual heterogeneity. Gene mutations are important predictive biomarkers that influence MM treatment decision. The aim of our study was to uncover the clinical significance of mutated genes in MM in the Chinese population. METHODS: Targeted exon panel sequencing was performed of 400 genes to detect the...

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PMID: 37406588
DOI: 10.1016/j.compbiomed.2023.107224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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