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Genomic characteristics and prognostic correlations in Chinese multiple myeloma patients

14 Mar 2025

Abstract excerpt

BACKGROUND: Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of abnormal clonal plasma cells in the bone marrow. The heterogeneity in Chinese MM populations remains underexplored. METHODS: We conducted whole-exome sequencing (WES) on 241 tumor samples, complemented by RNA sequencing (RNA-seq) on 131 samples from 212 Chinese MM patients. RESULTS: We identified a novel mutational...

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PMID: 40087669
DOI: 10.1186/s12920-025-02116-5

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