Article
[IL-33 gene recombination and expression does not affect the phenotypic characteristics of rabies virus in vitro].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Jul 2023
Gao Ting, Mi Zhizhong, Sun Ming, Tang Ximin, Wang Yong, Li Yingying
Abstract excerpt
Objective To create a recombinant rabies virus overexpressing IL-33 and to clarify the effect of IL-33 overexpression on the phenotypic characteristics of recombinant virus in vitro. Methods The IL-33 gene was obtained and amplified from the brain of a highly virulent strain of rabies infected mouse. It was then inserted between the G and L genes of the parental virus LBNSE genome by reversing genetic...
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