Article
Spread and pathogenic characteristics of a G-deficient rabies virus recombinant: an in vitro and in vivo study
1 Sept 2000
Abstract excerpt
Rabies virus (RV), a highly neurotropic enveloped virus, is known to spread within the CNS by means of axonal transport. Although the envelope spike glycoprotein (G) of cell-free virions is required for attachment to neuronal receptors and for virus entry, its necessity for transsynaptic spread remains controversial. In this work, a G gene-deficient recombinant RV (SAD delta G) complemented phenotypically with RV...
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