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Article

Role of hypoxia in cellular senescence

28 Jun 2023

Abstract excerpt

Senescent cells persist and continuously secrete proinflammatory and tissue-remodeling molecules that poison surrounding cells, leading to various age-related diseases, including diabetes, atherosclerosis, and Alzheimer’s disease. The underlying mechanism of cellular senescence has not yet been fully explored. Emerging evidence indicates that hypoxia is involved in the regulation of cellular senescence....

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PMID: 37385572
DOI: 10.1016/j.phrs.2023.106841

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