Article
Decreased miR-17-92 Cluster Correlates With the Senescent Features and Disrupted Oxidative Homeostasis, and the Impaired Therapeutic Efficacy of Adipose Tissue-derived Mesenchymal Stem Cells
2022-02-11
Abstract excerpt
<title>Abstract</title> <p><bold>Background: </bold>Aging and replicative cellular senescence is associated with the reduced therapeutic potential of mesenchymal stem cells (MSCs) on variety of diseases. This study aimed to determine the mechanism in regulating MSC senescence and further explore a modification strategy to reverse the senescence-associated cell dysfunction for improving the therapeutic efficacy of...
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Identifiers and source
- Literature Corpus work
- 10342c4a-b4b2-5350-9b12-2a110e4757a6
- DOI
- 10.21203/rs.3.rs-1333637/v1
