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Hypoxia and aging: molecular mechanisms, diseases, and therapeutic targets

15 Oct 2024

Abstract excerpt

Aging is a complex biological process characterized by the gradual decline of cellular functions, increased susceptibility to diseases, and impaired stress responses. Hypoxia, defined as reduced oxygen availability, is a critical factor that influences aging through molecular pathways involving hypoxia-inducible factors (HIFs), oxidative stress, inflammation, and epigenetic modifications. This review explores the...

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PMID: 39415849
DOI: 10.1002/mco2.786

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