Article
High Wnt2 Expression Confers Poor Prognosis in Colorectal Cancer, and Represents a Novel Therapeutic Target in BRAF-Mutated Colorectal Cancer.
Medicina (Kaunas, Lithuania) - 12 Jun 2023
Liu Huan, Zhang Lihua, Wang Ye, Wu Rendi, Shen Chenjie, Li Guifang, Shi Shiqi, Mao Yong, Hua Dong
Abstract excerpt
Background and Objectives: We aimed to investigate the role of Wnt2 expression in colorectal cancer (CRC) prognosis and evaluate its potential as a therapeutic target in BRAF-mutated CRC. Materials and Methods: Exactly 136 samples of formalin-fixed paraffin-embedded CRC tissue specimens were obtained from patients who underwent surgical resection for CRC. The gene mutation status of the samples was detected using...
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