Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic strategies targeting Wnt/β‑catenin signaling for colorectal cancer (Review).

International journal of molecular medicine - 1 Jan 2022

Ji Yong, Lv Jian, Sun Di, Huang Yufeng

Abstract excerpt

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress has been made in recent years, CRC survival remains unsatisfactory due to high metastasis and recurrence. Understanding the underlying molecular mechanisms of CRC tumorigenesis and metastasis has become increasingly important. Recently, aberrant Wnt/β‑catenin signaling has been reported to be strongly associated with CRC...

Topics

Join the communities discussing this publication.

Antineoplastic Agents
Apoptosis
beta Catenin
Colorectal Neoplasms
Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Targeted Therapy

RNA, Untranslated

Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 34713301
DOI: 10.3892/ijmm.2021.5056
PMCID: PMC8589460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic strategies targeting Wnt/β‑catenin signaling for colorectal cancer (Review).PMID 34713301Read ↗

Blocking the Wnt/β‑catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies (Review)Semantic proximity Read ↗

Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)Semantic proximity Read ↗

The potential of targeting Wnt/β-catenin in colon cancerSemantic proximity Read ↗

Wnt signaling in colorectal cancer: pathogenic role and therapeutic targetSemantic proximity Read ↗

Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.Semantic proximity Read ↗

Wnt/β Catenin-Mediated Signaling Commonly Altered in Colorectal Cancer.Semantic proximity Read ↗

Wnt signaling as a therapeutic target for cancer.Semantic proximity Read ↗

Tumor microenvironment involvement in colorectal cancer progression via Wnt/β-catenin pathway: Providing understanding of the complex mechanisms of chemoresistanceSemantic proximity Read ↗

Interaction between Wnt/β-catenin pathway and microRNAs regulates epithelial-mesenchymal transition in gastric cancer (Review)Semantic proximity Read ↗

Advances of Wnt Signalling Pathway in Colorectal CancerSemantic proximity Read ↗

Clinical Importance of Wnt5a in the Pathogenesis of Colorectal CancerSemantic proximity Read ↗

Targeting the Wnt/β-catenin signal pathway for the treatment of gastrointestinal cancer: Potential for advancementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.