Article
Overexpression of WNT2 and TSG101 genes in colorectal carcinoma.
Tropical biomedicine - 1 Apr 2008
Ma X R, Edmund Sim U H, Pauline B, Patricia L, Rahman J
Abstract excerpt
Colorectal carcinoma (CRC) arises as a result of mutational activation of oncogenes coupled with inactivation of tumour suppressor genes. Mutations in APC, K-ras and p53 have been commonly reported. In a previous study by our group, the tumour susceptibility gene 101 (TSG101) were found to be persistently upregulated in CRC cases. TSG101 was reported to be closely related to cancers of the breast, brain and...
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