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Article

Identification of New Potential Prognostic and Predictive Markers in High-Grade Osteosarcoma Using Whole Exome Sequencing.

International journal of molecular sciences - 13 Jun 2023

Gaeta Raffaele, Morelli Mariangela, Lessi Francesca, Mazzanti Chiara Maria, Menicagli Michele, Capanna Rodolfo, Andreani Lorenzo, Coccoli Luca, Aretini Paolo, Franchi Alessandro

Abstract excerpt

Conventional high-grade osteosarcoma (OS) is the most common primary cancer of bone and it typically affects the extremities of adolescents. OS has a complex karyotype, and molecular mechanisms related to carcinogenesis, progression and resistance to therapy are still largely unknown. For this reason, the current standard of care is associated with considerable adverse effects. In this study, our aim was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37373240
DOI: 10.3390/ijms241210086
PMCID: PMC10298506

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