Article

Molecular Subtyping of Early-Stage Osteosarcoma: Identifying Resistance and Optimizing Therapy

2025-03-13

Abstract excerpt

<h4>Background: </h4> Osteosarcoma (OS) is a highly aggressive primary bone malignancy, for which treatment and prognosis remain unchanged for three decades. This study aimed to delineate molecular subtypes of early-stage, treatment-naive OS to improve molecular stratification and guide precise therapeutic strategies. <h4>Methods:</h4> The top 10% of the most variable genes of 102 OS tumour tissues were used in NM...

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Literature Corpus work: 5acd4ad0-a5cb-5b61-a81d-6be99918e774
DOI: 10.20944/preprints202503.1009.v1

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