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Article

Whole exome sequencing of a single osteosarcoma case--integrative analysis with whole transcriptome RNA-seq data.

Human genomics - 11 Dec 2014

Reimann Ene, Kõks Sulev, Ho Xuan Dung, Maasalu Katre, Märtson Aare

Abstract excerpt

BACKGROUND: Osteosarcoma (OS) is a prevalent primary malignant bone tumour with unknown etiology. These highly metastasizing tumours are among the most frequent causes of cancer-related deaths. Thus, there is an urgent need for different markers, and with our study, we were aiming towards finding novel biomarkers for OS. METHODS: For that, we analysed the whole exome of the tumorous and non-tumour bone tissue...

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Source

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Identifiers

PMID: 25496518
DOI: 10.1186/s40246-014-0020-0
PMCID: PMC4272536

Genes

CDC27
IGF1
IGF2
MUC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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