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Article

The Clinical Implications of Tumor Mutational Burden in Osteosarcoma

7 Apr 2021

Abstract excerpt

Background Osteosarcoma (OTS) is aggressive bone malignancy without well-recognized prognosis biomarker. Tumor mutational burden (TMB) has been proved as effective biomarker in predicting clinical outcomes in several cancer types. However, its prognostic value in OTS remains unknown. In this study, we aim to evaluate the implication of TMB in OTS patients. Methods To depict the landscape of somatic mutations in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33898301
DOI: 10.3389/fonc.2020.595527

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