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Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma

16 Jun 2023

Abstract excerpt

Glioblastoma (GBM) is an aggressive and incurable primary brain tumor that harbors therapy-resistant cancer stem cells (CSCs). Due to the limited effectiveness of conventional chemotherapies and radiation treatments against CSCs, there is a critical need for the development of innovative therapeutic approaches. Our previous research revealed the significant expression of embryonic stemness genes, NANOG and OCT4,...

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PMID: 37372456
DOI: 10.3390/genes14061276

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