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Emerging targets for glioblastoma stem cell therapy

1 Jan 2016

Abstract excerpt

Glioblastoma multiforme (GBM), designated as World Health Organization (WHO) grade IV astrocytoma, is a lethal and therapy-resistant brain cancer comprised of several tumor cell subpopulations, including GBM stem cells (GSCs) which are believed to contribute to tumor recurrence following initial response to therapies. Emerging evidence demonstrates that GBM tumors are initiated from GSCs. The development and use...

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PMID: 26616589
DOI: 10.7555/jbr.30.20150100

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