Article

Mutation at position 5628 in the mitochondrial tRNAAla gene in a Chinese pedigree with maternally diabetes mellitus

2019-11-26

Abstract excerpt

<title>Abstract</title> <p>Background: To investigate the clinical, genetic and molecular characteristics of mitochondrial diabetes mellitus (MDM). <h4>Methods:</h4> Resultant variants were evaluated for evolutionary conservation, allelic frequencies, and structural and functional consequences. The mitochondrial function including mitochondrial tRNAAla levels, protein synthesis, membrane potential, adenosine trip...

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Literature Corpus work: b60f2c0b-1de8-5afe-8c2c-61894cee5d6c
DOI: 10.21203/rs.2.17444/v1

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