Article
Melanocortin-4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats.
Animal genetics - 1 Oct 2023
Jerjen C P, Kumaran S J, Liesegang A, Hall E, Wichert B, Haase B
Abstract excerpt
Obesity is an escalating global health problem affecting both humans and companion animals. In cats it is associated with increased mortality and multiple diseases, including diabetes mellitus. Two genes coding for proteins known to play a critical role in energy homeostasis across species are the proopiomelanocortin (POMC) gene and the melanocortin-4 receptor (MC4R) gene. A missense variant in the coding...
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