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Article

SNPs of melanocortin 4 receptor (MC4R) associated with body weight in Beagle dogs.

Experimental animals - 1 Jan 2014

Zeng Ruixia, Zhang Yibo, Du Peng

Abstract excerpt

Melanocortin 4 receptor (MC4R), which is associated with inherited human obesity, is involoved in food intake and body weight of mammals. To study the relationships between MC4R gene polymorphism and body weight in Beagle dogs, we detected and compared the nucleotide sequence of the whole coding region and 3'- and 5'- flanking regions of the dog MC4R gene (1214 bp). In 120 Beagle dogs, two SNPs (A420C, C895T)...

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Identifiers

PMID: 24521865
DOI: 10.1538/expanim.63.73
PMCID: PMC4160929

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