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Article

A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats.

PloS one - 1 Jan 2021

Forcada Yaiza, Boursnell Mike, Catchpole Brian, Church David B

Abstract excerpt

Diabetes mellitus (DM) is a common feline endocrinopathy, which is similar to human type 2 diabetes (T2DM) in terms of its pathophysiology. T2DM occurs due to peripheral insulin resistance and/or β-cell dysfunction. Several studies have identified genetic and environmental factors that contribute to susceptibility to human T2DM. In cats, environmental factors such as obesity and physical inactivity have been...

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Identifiers

PMID: 34874954
DOI: 10.1371/journal.pone.0259939
PMCID: PMC8651108

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