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Article

The Canine POMC Gene, Obesity in Labrador Retrievers and Susceptibility to Diabetes Mellitus.

Journal of veterinary internal medicine - 1 Mar 2017

Davison L J, Holder A, Catchpole B, O'Callaghan C A

Abstract excerpt

BACKGROUND: Diabetes mellitus (DM) in dogs is a common endocrinopathy with a complex genetic architecture. Disease susceptibility in several breeds is associated with polymorphisms in immune response genes, but in the Labrador retriever breed, no genetic associations with DM have been identified. A deletion in the pro-opiomelanocortin (POMC) gene in Labrador retrievers is associated with increased appetite and...

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Identifiers

PMID: 28176381
DOI: 10.1111/jvim.14636
PMCID: PMC5354034

Genes

POMC

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