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Article

Polymorphism and methylation of the MC4R gene in obese and non-obese dogs.

Molecular biology reports - 1 Aug 2017

Mankowska Monika, Nowacka-Woszuk Joanna, Graczyk Aneta, Ciazynska Paulina, Stachowiak Monika, Switonski Marek

Abstract excerpt

The dog is considered to be a useful biomedical model for human diseases and disorders, including obesity. One of the numerous genes associated with human polygenic obesity is MC4R, encoding the melanocortin 4 receptor. The aim of our study was to analyze polymorphisms and methylation of the canine MC4R in relation to adiposity. Altogether 270 dogs representing four breeds predisposed to obesity: Labrador...

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Identifiers

PMID: 28755272
DOI: 10.1007/s11033-017-4114-3
PMCID: PMC5579139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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