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Article

A polymorphism in the melanocortin 4 receptor gene (MC4R:c.92C>T) is associated with diabetes mellitus in overweight domestic shorthaired cats.

Journal of veterinary internal medicine - 1 Jan 2000

Forcada Y, Holder A, Church D B, Catchpole B

Abstract excerpt

BACKGROUND: Feline diabetes mellitus (DM) shares many pathophysiologic features with human type 2 DM. Human genome-wide association studies have identified genes associated with obesity and DM, including melanocortin 4 receptor (MC4R), which plays an important role in energy balance and appetite regulation. HYPOTHESIS/OBJECTIVES: To identify single nucleotide polymorphisms (SNPs) in the feline MC4R gene and to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 4

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Identifiers

PMID: 24372947
DOI: 10.1111/jvim.12275
PMCID: PMC4857971

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