Confirmation that a deletion in the POMC gene is associated with body weight of Labrador Retriever dogs.

doi:10.1016/j.rvsc.2017.02.014

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Article

Confirmation that a deletion in the POMC gene is associated with body weight of Labrador Retriever dogs.

Research in veterinary science - 1 Jun 2017

Mankowska M, Krzeminska P, Graczyk M, Switonski M

Abstract excerpt

A 14-bp deletion present in the proopiomelanocortin (POMC) gene of Labrador and Flat Coat Retrievers (FCR), but absent in POMC of other breeds, disrupts the β-MSH and β-endorphin coding sequences. This deletion was recently reported as strongly associated with increased body weight and obesity. We searched for this mutation in a cohort of 272 dogs, representing four breeds with a known predisposition to obesity...

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Identifiers

PMID: 28235700
DOI: 10.1016/j.rvsc.2017.02.014

Genes

POMC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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