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[Pathophysiology and treatment of adult Langerhans cell histiocytosis].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2020

Tojo Arinobu, Kobayashi Masayuki

Abstract excerpt

Langerhans cell histiocytosis (LCH) is a rare disease characterized by tissue infiltration of clusters of CD1a+/CD207+ histiocyte-like cells and a resultant surrounding inflammatory reaction. Because of its morphological similarity to cutaneous Langerhans cells, LCH was formerly named histiocytosis X in 1987. However, its cell lineage appears closely related to myeloid dendritic cells. In 2010, BRAF-V600E was...

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Identifiers

PMID: 33162496
DOI: 10.11406/rinketsu.61.1028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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