Clinical and prognostic characteristics of 95 cases of Langerhans cell histiocytosis in children: a single-institute experience from 2013 to 2020.

doi:10.1080/07853890.2021.1966085

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Article

Clinical and prognostic characteristics of 95 cases of Langerhans cell histiocytosis in children: a single-institute experience from 2013 to 2020.

Annals of medicine - 1 Dec 2021

Tang Xue, Gao Ju, Ma Zhi-Gui, Guo Xia, Li Qiang, Wan Zhi, Sun Jing-Jing

Abstract excerpt

BACKGROUND: This study aimed to understand the clinical characteristics and outcomes of children with Langerhans cell histiocytosis (LCH) in China. METHODS: We conducted a retrospective study of 95 paediatric patients with LCH in West China Second University Hospital of Sichuan University between...

Topics

Antineoplastic Combined Chemotherapy Protocols
Child
Cytarabine
Histiocytosis, Langerhans-Cell
Humans
MAP Kinase Kinase 1
MAP Kinase Signaling System
Mutation
Prednisone
Prognosis
Prospective Studies
Proto-Oncogene Proteins B-raf
Retrospective Studies
Vemurafenib

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Identifiers

PMID: 34459688
DOI: 10.1080/07853890.2021.1966085
PMCID: PMC8409935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34459688-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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