Article
Genetic Influence of CCDC63 Polymorphisms on Alcohol-Induced Dyslipidemia in a Korean Cohort.
International journal of molecular sciences - 25 Feb 2026
Kim Yu-Na, Lee Sung Won, Jin Hyun-Seok, Park Sangwook
Abstract excerpt
While chronic alcohol consumption is an established risk factor for lipid metabolic dysregulation, the underlying genetic mediators remain largely elusive. This study investigated the synergistic impact of CCDC63 (coiled-coil domain containing 63) polymorphisms and alcohol intake on dyslipidemia risk within a Korean cohort. Leveraging data from the KARE study (N = 6655; 4327 dyslipidemia cases vs. 2328 controls),...
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