Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study of comorbid depressive syndrome and alcohol dependence.

Psychiatric genetics - 1 Feb 2012

Edwards Alexis C, Aliev Fazil, Bierut Laura J, Bucholz Kathleen K, Edenberg Howard, Hesselbrock Victor, Kramer John, Kuperman Samuel, Nurnberger John I, Schuckit Marc A, Porjesz Bernice, Dick Danielle M

Abstract excerpt

OBJECTIVE: Depression and alcohol dependence (AD) are common psychiatric disorders that often co-occur. Both disorders are genetically influenced, with heritability estimates in the range of 35-60%. In addition, evidence from twin studies suggests that AD and depression are genetically correlated. Herein, we report results from a genome-wide association study of a comorbid phenotype, in which cases meet the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comorbidity

Share to Depressive Disorder

Share to Gene Expression Regulation

Share to Genetic Markers

Share to Genome-Wide Association Study

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 22064162
DOI: 10.1097/YPG.0b013e32834acd07
PMCID: PMC3241912

Genes

CDH13
CSMD2
GRID1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study of comorbid depressive syndrome and alcohol dependence.PMID 22064162Read ↗

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Semantic proximity Read ↗

Shared genetic etiology between alcohol dependence and major depressive disorder.Semantic proximity Read ↗

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.Semantic proximity Read ↗

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortiumSemantic proximity Read ↗

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.Semantic proximity Read ↗

Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence.Semantic proximity Read ↗

Genetics of Alcohol Dependence: A Review of Clinical StudiesSemantic proximity Read ↗

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder.Semantic proximity Read ↗

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).Semantic proximity Read ↗

Genome-wide association study of alcohol dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.