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Article

A computational study of the R120G mutation in human αB-crystallin: implications for structural stability and functionality.

Journal of biomolecular structure & dynamics - 1 Jul 2024

Darvazi Mona, Ghorbani Mohammad, Ramazi Shahin, Allahverdi Abdollah, Abdolmaleki Parviz

Abstract excerpt

The eye is a vital organ in the visual system, which is composed of transparent vascular tissue. αB-crystallin, a significant protein found in the lens, plays a crucial role in our understanding of lens diseases. Mutations in the αB-crystallin protein can cause lens diseases, such as cataracts and myopathy. However, the molecular mechanism underlying the R120G mutation is not fully understood. In this study, we...

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Identifiers

PMID: 37354135
DOI: 10.1080/07391102.2023.2229434

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ACD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A computational study of the R120G mutation in human αB-crystallin: implications for structural stability and functionality.PMID 37354135Read ↗

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