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Article

The Association Between Autoimmune Rheumatic Diseases and Depression: A Two-Sample Bidirectional Mendelian Randomization.

Psychiatry - 1 Jan 2026

Wang Huiying, Wang Youqing, Xu Yujia

Abstract excerpt

BackgroundAlthough prior observational studies have indicated an association between depression and autoimmune rheumatic diseases (ARDs), the underlying causal relationship remains unclear. Methods: A two-sample bidirectional Mendelian randomization (MR) study was conducted to explore the causal link between depression and ARDs. Genetic data for both depression and ARDs were obtained from publicly available...

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PMID: 40705971
DOI: 10.1080/00332747.2025.2528526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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