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Article

Major depression disorder may causally associate with the increased breast cancer risk: Evidence from two-sample mendelian randomization analyses.

Cancer medicine - 1 Jan 2023

Ren Qian, Luo Fangxiu, Ge Sheng, Chen Peizhan

Abstract excerpt

INTRODUCTION: Major depression disorder (MDD) has been associated with increased breast cancer risk in epidemiological studies; however, it is still unknown whether this association is causal or not. The aim of this study is to determine the causal relationship between MDD and breast cancer risk. METHODS: Two-sample Mendelian randomization (MR) analyses with 92 single-nucleotide polymorphisms (SNPs) significantly...

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PMID: 35852181
DOI: 10.1002/cam4.5043
PMCID: PMC9883582

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