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Article

ELAC2 is a functional prostate cancer risk allele.

Trends in molecular medicine - 1 Aug 2023

Blinka Steven, Mishra Rashmi, Hsieh Andrew C

Abstract excerpt

Stentenbach and colleagues have unveiled a functional role of a human germline mutation found in the ribonuclease (RNase) Z enzyme, ELAC2, in prostate cancer. Here, we discuss the importance of these findings in enhancing our understanding of how risk variants enable prostate cancer progression and the post-transcriptional mechanisms underlying oncogenesis.

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Identifiers

PMID: 37353407
DOI: 10.1016/j.molmed.2023.06.002
PMCID: PMC10527048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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