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Article

Structure of primate and rodent orthologs of the prostate cancer susceptibility gene ELAC2.

Biochimica et biophysica acta - 17 Sept 2004

Dumont Martine, Frank David, Moisan Anne-Marie, Tranchant Martine, Soucy Penny, Breton Rock, Labrie Fernand, Tavtigian Sean V, Simard Jacques

Abstract excerpt

The human ELAC2 gene was the first candidate prostate cancer susceptibility gene identified by linkage analysis and positional cloning. DNA sequence indicates a protein of 826 amino acids encoded by 24 exons. In the present study, we characterized the coding sequence of chimpanzee and gorilla ELAC2 orthologs by direct sequencing of genomic fragments, and of cynomolgus monkey and rat orthologs by screening cDNA...

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Source

Identifiers

PMID: 15358515
DOI: 10.1016/j.bbaexp.2004.07.001

Genes

ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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