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Article

The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex.

International journal of cancer - 10 Apr 2003

Korver Wouter, Guevara Claudia, Chen Yang, Neuteboom Saskia, Bookstein Rob, Tavtigian Sean, Lees Emma

Abstract excerpt

ELAC2 is a novel candidate cancer susceptibility gene located on chromosome 17p: Carriers of mutations in ELAC2 display a higher risk of developing prostate cancer. Overexpression of ELAC2 in tumor cells causes a delay in G2-M progression characterized by accumulation of cyclin B levels. Consistent with a function in mitosis, further biochemical analysis revealed that ELAC2 physically interacts with the...

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Share to Adenoviridae
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12569551
DOI: 10.1002/ijc.10945

Genes

ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex.PMID 12569551Read ↗

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