Article
A Vicious Circle of Clonal Haematopoiesis of Indeterminate Potential and Cardiovascular Disease.
Hamostaseologie - 1 Dec 2021
Ehlert Carolin A, Hilgendorf Ingo
Abstract excerpt
Clonal haematopoiesis of indeterminate potential (CHIP) represents a recently identified overlap between cancer and cardiovascular disease (CVD). CHIP develops as a result of certain acquired somatic mutations that predispose to leukaemia, but clinically even more prevalent, associate with increased risk for CVD and CVD-related death. Experimental studies suggest a causal role for CHIP aggravating inflammatory...
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