Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phaeomelanin synthesis and obesity in mice. Interaction of the viable yellow (Avy) and sombre (eso) mutations.

The Journal of heredity - 1 Jan 2000

Wolff G L, Galbraith D B, Domon O E, Row J M

Abstract excerpt

Is abnormal regulation of phaeomelanin synthesis, which results in yellow coat color, inextricably linked to the development of obesity in viable yellow (Avy) house mice? To answer this question, black male mice of genotypes Avy/A eso/e+ and A/ae eso/e+ were produced from (DFT/Wf X C3H-1 vyfB/HeWf X SO/LeWf matings. The sombre (eso) mutation prevents phaeomelanin synthesis; therefore, all mice carrying this...

Topics

Animals
Crosses, Genetic
Genes
Melanins
Mice
Mice, Inbred CBA
Mice, Inbred Strains
Mice, Obese
Mutation
Obesity
Phenotype
Pigmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 744871
DOI: 10.1093/oxfordjournals.jhered.a108953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-744871-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phaeomelanin synthesis and obesity in mice. Interaction of the viable yellow (Avy) and sombre (eso) mutations.PMID 744871Read ↗

Prenatal determination of obesity, tumor susceptibility, and coat color pattern in viable yellow (Avy/a) mice. The yellow mouse syndrome.Semantic proximity Read ↗

Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene.Semantic proximity Read ↗

Neomorphic agouti mutations in obese yellow mice.Semantic proximity Read ↗

Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female.Semantic proximity Read ↗

Effects of post-weaning diet on metabolic parameters and DNA methylation status of the cryptic promoter in the A(vy) allele of viable yellow mice.Semantic proximity Read ↗

Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles.Semantic proximity Read ↗

Epigenetic inheritance at the agouti locus in the mouse.Semantic proximity Read ↗

Genetic studies of the mouse mutations mahogany and mahoganoid.Semantic proximity Read ↗

Molecular basis of the pleiotropic phenotype of mice carrying the hypervariable yellow (Ahvy) mutation at the agouti locus.Semantic proximity Read ↗

Coat color genetics of Peromyscus. I. Ashiness, an age-dependent coat color mutation in the deer mouse.Semantic proximity Read ↗

Dose-response effects of ectopic agouti protein on iron overload and age-associated aspects of the Avy/a obese mouse phenome.Semantic proximity Read ↗

Effects of the lethal yellow (Ay) mutation in mouse aggregation chimeras.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.