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Article

ICOS gene polymorphisms in systemic lupus erythematosus: A case-control study.

International journal of immunogenetics - 1 Aug 2023

Houssaini Hana, Bouallegui Emna, Abida Olfa, Tahri Safa, Elloumi Nesrine, Hachicha Hend, Marzouk Sameh, Bahloul Zouhir, Masmoudi Hatem, Fakhfakh Raouia

Abstract excerpt

The inducible T-cell costimulator (ICOS) may play an important role in adaptive immunity by regulating the interaction between T cells and antigen-presenting cells. Disruption of this molecule can lead to autoimmune diseases, in particular systemic lupus erythematosus (SLE). In this study, we aimed to explore the possible association between ICOS gene polymorphisms and SLE as well as their influence on disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37338463
DOI: 10.1111/iji.12625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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