Article
High plasma interleukin-6 level, but not IL-6 gene variants, as a predictive marker for the development of hepatocellular carcinoma in a Moroccan population.
International journal of immunogenetics - 1 Aug 2024
Tanouti Ikram-Allah, Fellah Hassan, Haddaji Asmaa, Zerrad Chaimaa, Tahiri Mohamed, Badre Wafaa, Nfaoui Khaoula, Pineau Pascal, Benjelloun Soumaya, Ezzikouri Sayeh
Abstract excerpt
Chronic inflammation triggered by hepatitis B (HBV) and hepatitis C (HCV) viruses elevates interleukin 6 (IL-6) levels, activating pathways that cause liver damage and contribute to hepatocellular carcinoma (HCC) development. In this study, we assessed IL-6 levels and explored the correlation between the rs1800795 and rs1800797 variants of the IL-6 gene and the risk of developing HCC. We conducted a case-control...
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