Article
NOD1 and NOD2 genetic variants: Impact on hepatocellular carcinoma susceptibility and progression in Moroccan population.
Gene - 30 Dec 2024
Zerrad Chaimaa, Lkhider Mustapha, Bouqdayr Meryem, Belkouchi Abdelkader, Badre Wafaa, Tahiri Mohamed, Pineau Pascal, Benjelloun Soumaya, Ezzikouri Sayeh
Abstract excerpt
BACKGROUND: Nucleotide-binding oligomerization domain 1 (NOD1) and NOD2 are involved in carcinogenic processes by recognizing bacterial cell wall components and triggering inflammation. This study explored the association between genetic variations in NOD1 and NOD2 and susceptibility to hepatocellular carcinoma (HCC) and its progression in a Moroccan population. METHODS: Genotyping of NOD1 rs2075820 (C>T) and...
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