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Prioritization and functional validation of target genes from single-cell transcriptomics studies

17 Jun 2023

Abstract excerpt

Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional validation, it remains challenging to know which markers truly exert the putative function. Given the lengthy/costly nature of validation studies, gene prioritization is...

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PMID: 37330599
DOI: 10.1038/s42003-023-05006-7

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