Article

PltScanner: A Lightweight Classifier for Accurate Platelet Annotation and Heterogeneity Discovery in scRNA-seq Data

2026-06-25

Abstract excerpt

<title>Abstract</title> <p>Single-cell RNA sequencing (scRNA-seq) has become a powerful approach for dissecting cellular composition and intercellular interactions in complex tissues. Platelets play essential roles in hemostasis and thrombosis and are increasingly recognized as important regulators of inflammation, immunity, and disease progression. However, because platelets are anucleate and contain low levels...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9d658351-9ae8-5981-b5ba-459a535e4d7f
DOI: 10.21203/rs.3.rs-9209612/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PltScanner: A Lightweight Classifier for Accurate Platelet Annotation and Heterogeneity Discovery in scRNA-seq DataDOI 10.21203/rs.3.rs-9209612/v1Read

The First Comprehensive Description of the Platelet Single Cell TranscriptomeSemantic proximity Read

A comprehensive platelet expression atlas (PEA) resource and platelet transcriptome landscapeSemantic proximity Read

Deciphering Abnormal Platelet Subpopulations in Inflammatory Diseases through Machine Learning and Single-Cell TranscriptomicsSemantic proximity Read

Toward platelet transcriptomics in cancer diagnosis, prognosis and therapySemantic proximity Read

ASURAT: functional annotation-driven unsupervised clustering of single-cell transcriptomesSemantic proximity Read

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics.Semantic proximity Read

PlateletBase: A Comprehensive Knowledgebase for Platelet Research and Disease InsightsSemantic proximity Read

RareCapsNet: An explainable capsule networks enable robust discovery of rare cell populations from large-scale single-cell transcriptomicsSemantic proximity Read

Patterns, Profiles, and Parsimony: dissecting transcriptional signatures from minimal single-cell RNA-seq output with SALSASemantic proximity Read

Prioritization and functional validation of target genes from single-cell transcriptomics studiesSemantic proximity Read

Key platelet genes play important roles in predicting the prognosis of sepsisSemantic proximity Read