Article

Inference of marker genes of subtle cell state changes via iterative logistic regression

2025-05-28

Abstract excerpt

We present iterative logistic regression (iLR) for the identification of small sets of informative marker genes. Differential expression and marker gene selection methods for single-cell RNA sequencing (scRNA-seq) data can struggle to identify small sets of informative genes, especially for subtle differences between cell states, as can be induced by disease or treatment. iLR applied logistic regression iterativel...

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Literature Corpus work: 0fadbccd-f455-563e-9c76-d5e4a4228d9d
DOI: 10.1101/2025.05.23.655858

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