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Article

A mathematical model for cancer risk and accumulation of mutations caused by replication errors and external factors.

PloS one - 1 Jan 2023

Uchinomiya Kouki, Tomita Masanori

Abstract excerpt

Replication errors influence mutations, and thus, lifetime cancer risk can be explained by the number of stem-cell divisions. Additionally, mutagens also affect cancer risk, for instance, high-dose radiation exposure increases lifetime cancer risk. However, the influence of low-dose radiation exposure is still unclear because this influence, if any, is very slight. We can assess the minimal influence of the...

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Identifiers

PMID: 37315031
DOI: 10.1371/journal.pone.0286499
PMCID: PMC10266611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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