Article
Intra-host mutation rate of acute SARS-CoV-2 infection during the initial pandemic wave.
Virus genes - 1 Oct 2023
El-Haddad Kim, Adhikari Thamali M, Tu Zheng Jin, Cheng Yu-Wei, Leng Xiaoyi, Zhang Xiangyi, Rhoads Daniel, Ko Jennifer S, Worley Sarah, Li Jing, Rubin Brian P, Esper Frank P
Abstract excerpt
SARS-CoV-2 mutation is minimized through a proofreading function encoded by NSP-14. Most estimates of the SARS-CoV-2 mutation rate are derived from population based sequence data. Our understanding of SARS-CoV-2 evolution might be enhanced through analysis of intra-host viral mutation rates in specific populations. Viral genome analysis was performed between paired samples and mutations quantified at allele...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.