Article
Molecular Basis and Hematologic Phenotype of Hemoglobin H Disease Combined with Two Rare β-Globin Mutations.
Hemoglobin - 1 Nov 2023
Qiu Yuling, Wei Shilu, Hou Wei, Lai Ketong, Zhu Hengying, Li Wenwei, Li Qi, Yang Zheng, Shu Qisheng, Chen Ping, Mo Wuning
Abstract excerpt
In area where α-thalassemia and β-thalassemia are prevalent, the coinheritance of hemoglobin H disease (Hb H disease) and β-thalassemia are not uncommon and could result in complex thalassemia intermedia syndromes. In this study, we investigate the hematological and molecular characteristics of two previously undescribed cases that co-inherited Hb H disease and rare β-globin gene (HBB) mutations found in Chinese...
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