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Elevated Hb A2 is Not Always Indicative of β-Thalassemia.

Hemoglobin - 1 May 2021

Luo Li-Ping, Ma Li, Lin Shao-Bin, Huang Jun-Gao

Abstract excerpt

Hb A2 levels are usually high in carriers of β-thalassemia (β-thal). These levels also provide a sensitive marker for the identification of hemoglobin (Hb) variants. In this study, we aimed to examine two patients from two Chinese families who showed elevated Hb A2 levels but did not show any signs of β-thal. The HBB variants were analyzed using direct sequencing of HBB and in silico prediction analysis....

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PMID: 34100337
DOI: 10.1080/03630269.2021.1936008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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