Article
[Genotypes and clinical features of 595 children with HbH disease in Guangxi, China].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Sept 2015
He Sheng, Zhang Qiang, Chen Bi-Yan, Huang Peng, Tang Yan-Qing, Wei Yuan, Chen Qiu-Li, Zheng Chen-Guang
Abstract excerpt
OBJECTIVE: To investigate the genotypes and clinical features of children with HbH disease in Guangxi Zhuang Autonomous Region, China. METHODS: A total of 595 children from Guangxi were recruited. Single-tube multiplex polymerase chain reaction combined with agarose gel electrophoresis, as well as reverse dot blotting, were performed to detect the three α-globin gene deletion mutations (--(SEA), -α(3.7), and...
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